Internship in Mechanistic Modelling for DSP Chromatography (m/f/d)

Work Your Magic with us!

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

Date de début:ASAP
Durée: 6 month-12 month

Lieu: Corsier-sur-Vevey, Suisse
Position:Internship

J ob Title:Internship in Mechanistic Modelling for DSP Chromatography

Business Context Pharma4.0 aims to accelerate medicine development and manufacturing through digitalization. Digital twins and mechanistic/hybrid/data models are central to this transformation. The internship focuses on developing predictive models for downstream drug substance development using mechanistic models. The goal is to test an experimental workflow for building predictive mechanistic models for chromatography, with experiments conducted at robotic scale and gPROMS used for data analysis. The model's robustness will be assessed and reported throughout the project.

Key Responsibilities

• Develop and refine predictive mechanistic/hybrid models for the downstream chromatography step.
• Translate experimental data into modeling parameters and validate model predictions.
• Design and run robotic-scale/AKTA scale experiments to calibrate and validate membrane chromatography models.
• Document modeling approaches, assumptions, and validation results; present to multidisciplinary teams.

Your Profile

• Pursuing a Master's in Chemical Engineering, Biotech Engineering, or equivalent; strong foundation in statistics, modeling, and ML.
• Familiarity with chromatography (capture and anionic chromatography, SEC-HPLC) and tools (CADET/Scikit or MATLAB);experience with gPROMS/Dynochem and DoE (JMP) is a plus.
• Comfortable with wet-lab work and integrating experimental data with models.
• Analytical, methodical, autonomous, and able to clearly communicate modeling results.
• Proficient in English.

What we offer:

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!